• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A blood filtration device includes a flexible housing (1) defining a receiving chamber (100) having first and second spaced interior surfaces (11, 12) defining the receiving chamber, and first and second second outer surfaces (13, 14) respectively opposed to the first and second inner surfaces (11, 12); and a filter-absorber element (2) disposed in the receiving chamber (100), cooperating with the first inner surface (11) to form an inlet guide channel (3) between the two, and cooperating with the second surface internal (12) for forming an outlet guide channel (4) between the two; an inlet tube (5) having a tip inserted into the first outer surface (13) of the flexible housing (1) so as to establish spatial communication with the inlet guide channel (3); and an outlet tube (6) having a tip inserted into the second outer surface (14) of the flexible housing (1) so as to establish spatial communication with the outlet guide channel (4).
    公开号:FR3028425A1
    申请号:FR1555837
    申请日:2015-06-24
    公开日:2016-05-20
    发明作者:Tien Chu Juan；Cheng Sheng Liang；Hsin Tai Ko；Yu Luen Chen；Ruei Jiun Yang；Pei Chieh Chuang；Yi Ying Yu；Yu Ping Chen；Jun Ming Chen
    申请人:SANGTECH LAB Inc；
    IPC主号:
    专利说明:

    [0001] This invention relates generally to a blood filtration device, more particularly to a blood filtration device which comprises a flexible housing adapted to withstand or withstand significant impact so as to avoid be damaged and break, and is capable of filtering unwanted waste into the blood so that the fresh blood components filtered therein are free of impurities that are harmful to human health. A blood filtration device is used in conjunction with a set of blood bag tubings. In recent years, whole blood is rarely administered in blood transfusion since it is known that whole blood is a mixture of cells, colloids and crystalloids which can be separated into different blood components, namely a concentrate of blood cells. PRBC packed red blood cells), platelet concentrate, fresh frozen plasma and cryoprecipitate. Each blood component is used for a different indication; thus, the separation of the components has maximized the use of a unit of whole blood. When a blood bank receives a pack of fresh blood from a donor, the fresh blood is separated by centrifugation into several packs containing different blood components, so that patients in need of red blood cells receive a concentrate of blood. Red blood cells and patients in need of platelets receive platelet concentrate. As a result, a bag of fresh blood from a donor, together with a blood filtration device, needs to be centrifuged in order to separate or deplete a certain amount of blood components, for example to deplete the content of blood components. in leukocytes in whole blood, and thus satisfies the current required standard for the transfusion of red blood cell concentrate, and collects clinical data for the evaluation or the performance of other functions or diagnosis. It is noted that during centrifugation, the blood filtration device can not avoid being struck by parts of the centrifugal machine and other input elements.
    [0002] A conventional blood filtration device generally comprises an outer casing or casing made from a hard plastic material, and a filter element disposed within the casing to provide fine filtration effects. Filtration of whole blood will cause the filter element to expand once the filter element is fully soaked with whole blood after a period of filtration treatment, thereby preventing a smooth blood circulation in the tubing assembly. and lowering the filtration quality. The above disadvantages are caused since the outer casing limits expansion of the filter element due to its hardness and lack of flexibility and deformation. In addition, when the entire blood bag assembly is disposed in the centrifuge machine for centrifugation, the blood filtering device can not avoid colliding with other centrifugal components, whereby Conventional blood filtration device tends to break and can not be used after centrifugation, its case made from a hard plastic being subject to fragmentation due to collision.
    [0003] In order to eliminate the disadvantages mentioned above, a blood filtration device has been developed, is commercially available and includes a flexible outer casing which is resistant to collisions and which does not break or deform after the centrifugation treatment. However, the filter element disposed within the flexible outer housing expands significantly once the entire outer casing is filled with whole blood during the filtration treatment, since this outer casing is incapable control or stop the expansion, thus preventing a smooth movement inside it. A main object of the present invention is to provide a blood filtration device to eliminate the disadvantages resulting from the use of prior art blood filtration devices. The present invention therefore relates to a blood filtration device for depleting a content of blood components in the blood, in particular in whole blood, which device is characterized in that it comprises: a flexible housing defining a receiving chamber 25 having first and second internally spaced apart surfaces defining the receiving chamber, and first and second outer surfaces respectively opposed to the first and second inner surfaces; and a filter-absorber element disposed in said receiving chamber, cooperating with said first inner surface to form an inlet guide channel between both, and cooperating with said second inner surface to form a guide channel of exit between the two; an inlet tube having a tip inserted into said first outer surface of said flexible housing so as to establish spatial communication with said inlet guide channel; and an outlet tube having a tip inserted into said second outer surface of the flexible housing so as to establish spatial communication with said outlet guide channel. A distinct feature of the present invention is the increased impact resistance of the flexible housing when the blood filtration device of the present invention is co-disposed with the fresh whole blood bag in the centrifuge machine. to prevent damage thereof in addition to controlling expansion of the filter-absorber element in the flexible housing. Preferably, the flexible housing expands slightly and simultaneously with the filter-absorber element so as to maintain a smooth blood circulation during the filtration treatment. In addition, the formation of fluid guide plates or fluid impeding protrusions within the flexible housing allows uniform blood to be uniformly diffused into the filter-absorber element, thereby maintaining the initial dimensions. inlet guide and exit guide tubes to allow smooth circulation in the blood filtration device of the present invention.
    [0004] Compared with the prior art blood filtration devices, the blood filtration device of the present invention is not only durable and highly impact resistant, but also has a better effect. filtration and a smooth blood circulation due to the flexible material from which the flexible housing is made. Said first internal surface may comprise a plurality of first fluid guide plates.
    [0005] Said second inner surface may comprise a plurality of second fluid guide plates. Said first internal surface may include a plurality of fluid impedance projections. Said filter-absorber element may be disposed in said flexible housing and have a peripheral portion connected to an inner peripheral portion of said flexible housing. Said filter-absorber element may have an outer peripheral portion exposed to an exterior of said flexible housing, the blood filtering device further comprising a flexible membrane wrapped around said flexible housing, having a peripheral portion integrally formed therewith outer peripheral portion of said filter-absorber element such that said flexible housing is fully encased in said flexible membrane. Said flexible housing may have an inner peripheral flexible membrane while said filter-absorber member may have an outer peripheral portion formed integrally with said inner peripheral flexible membrane of said flexible housing such that said filter-absorber element is disposed in said flexible housing.
    [0006] Said first outer surface of said flexible housing may include an inlet guide seat projecting outwardly therefrom such that said tip of said inlet tube is integral with said guide seat. Entrance. Said second outer surface of said flexible housing may include an outlet guide seat projecting outwardly therefrom, such that said tip of said outlet tube is integral with said inlet guide seat. The flexible housing can be made from a flexible plastic material. The flexible housing can be made from an ethylene / vinyl acetate copolymer resin (EVA). The flexible housing can be made from poly (ethylene terephthalate) (PET). The flexible housing (1) can be made from polyvinyl chloride (PVC).
    [0007] The accompanying drawings are presented to provide a better understanding of the invention, and are incorporated in and form part of the specification. The drawings illustrate embodiments of the invention and, together with the description, serve to explain the principles of the invention. Figure 1 is a perspective view of a first embodiment of a blood filtration device of the present invention; Figure 2 shows a perspective view in partial section of the first embodiment of the blood filtration device of the present invention; Figure 3 shows a perspective view of a second embodiment of the blood filtration device of the present invention; and Figure 4 shows a perspective view in partial section of a third embodiment of the blood filtration device of the present invention.
    [0008] Referring to FIGS. 1 and 2, it can be seen that FIG. 1 is a perspective view of the first embodiment of a blood filtration device of the present invention; and that Figure 2 shows a perspective view in partial section of the first embodiment of the blood filtration device of the present invention. As shown, a blood filtration device 10 of the present invention, for depleting a blood component content (such as a concentration of leukocytes) in whole blood, comprises a flexible housing 1, a filter-absorber element 2 , an inlet tube 5 and an outlet tube 6. The flexible housing 1 defines a receiving chamber 100, has first and second circular inner surfaces 11, 12 defining the receiving chamber 100, and first and second surfaces. circular outer members 13, 14 opposed respectively to the first and second circular inner surfaces 11, 12. The filter-absorber element 2 is disposed in the receiving chamber 100, cooperates with the first inner surface 11 to form a guide channel of inlet 3 between the two, and cooperates with the second inner surface 12 to form an outlet guide channel 4 between the two. The inlet tube 5 has a tip 8 introduced into the first outer surface 13 of the flexible housing 1 so as to establish spatial communication with the inlet guide channel 3. The outlet tube 6 has a tip inserted into the second outer surface 14 of the flexible housing 1 so as to establish spatial communication with the outlet guide channel 4. Referring again to Figure 1, it can be seen that the first inner surface 11 of the flexible housing 1 has a plurality of first fluid guide plates 111 such that once the inlet tube 5 guides the blood into the inlet guide channel 3, the guide plates 111 are able to uniformly diffuse. the blood in the filter-absorber element 2. Referring again to FIG. 2, it can be seen that the second inner surface 12 of the flexible housing 1 has a plurality of second fluid-guiding plates 121 so that a After the blood has passed through the filter-absorber element 2, the second fluid guide plates 121 guide the filtered blood uniformly outwardly into the outlet guide channel 6, thereby improving the filtration treatment. . Note that in the case of an expansion of the adsorbing filter element 2 due to the filtration treatment, the first and second guide plates 111, 121 can co-operatively maintain the size of the inlet guide channels and 3, 4, to improve the smooth circulation of blood in the blood filtration device 10 of the present invention. It should be noted that the first and second guide plates 111, 121 in this embodiment are constituted by a plurality of curved plate sections. However, the configuration of these plates should not be limited only to the one just indicated, but should include other configurations as long as they can guide the blood smoothly and evenly throughout the body. filter-absorber element 2 and subsequently guide the filtered blood into the outlet guide channel 4. It is noted that after the filter-absorber element 2 is disposed in the receiving chamber 100, the filter-absorber element 2 has an outer peripheral portion connected or formed integrally with an inner peripheral portion of the flexible housing 1 so that the blood guided in the inlet guide channel 3 can not flow into the output guide 4 without passing through the filter-absorber element 2. Preferably, the first circular outer surface 13 of the flexible housing 1 has an inlet guide seat 131 projecting outwards and adiale from the periphery delimiting the first circular outer surface so that the tip of the inlet tube 5 is integrated into the inlet guide seat 131. Similarly, the second circular outer surface 14 of the flexible housing 1 has an outlet guide seat 131 protruding outwardly and radially from the periphery so that the tip of the outlet tube 6 is integrated into the inlet guide seat 131, thereby facilitating the assembly of the blood filtration device of the present invention with respect to a blood bag (not shown). Figure 3 shows a perspective view of the second embodiment of the blood filtration device of the present invention. The structure of the second embodiment is similar to the first embodiment, except that the first inner surface 11 of the flexible housing 1 has a plurality of fluid impeding protrusions 113 which perform the same function as the first guide plates 111. In other words, the fluid impeding protrusions 113 are capable of uniformly diffusing the blood into the filter-absorber element 2. The flexible housing 1 in the first and second embodiments is preferably manufactured at From a flexible plastic material, such that the flexible housing 1 is able to withstand a collision or impact during the centrifugation process. Figure 4 shows a perspective view in partial section of the third embodiment of the blood filtration device of the present invention. The structure of the third embodiment is similar to the second embodiment, except that the filter-absorber element 2 has an outer peripheral portion exposed to an outside of the flexible housing 1. A flexible membrane 7 is wrapped around the flexible housing 1 has an outer peripheral portion formed integrally with the outer peripheral portion of the filter element (2) so that the flexible housing (1) is fully and hermetically sealed and thus enclosed within the flexible membrane (7). such that the tips of the inlet guide tube 5 and the outlet guide tube 6 are integral with the flexible membrane 7 so as to establish spatial communication with the inlet guide channel respectively. 3 and the outlet guide channel 4. The blood filtration device 10 of the present invention thus manufactured is lightweight in addition to being capable of to withstand a strong collision or a strong impact. In the case where the flexible housing 1 is made from a flexible material of inferior quality and is subject to deformation, and where the flexible membrane 7 is made from a flexible material of superior quality, such The arrangement can prevent a break between the flexible housing 1 and the filter-absorber element 2 due to a different material of manufacture when a strong collision or impact is applied to the flexible membrane 7. As in the previous embodiment the formation of the first and second guide plates 111, 121 on the first and second inner surfaces 11, 12 of the flexible housing 1 is intended to maintain the initial dimensions of the inlet guide and outlet guide channels 3, 4 when the filter-absorber element 2 expands during the blood filtration treatment. In addition, since the tips of the inlet and outlet tubes 5, 6 are hermetically sealed with the flexible membrane 7, the blood inside the inlet and outlet tubes 5, 6 will not leak. Due to an easy deformation of the flexible membrane 7. In other words, when the blood filtration device 10 made according to the third embodiment is struck by the front and the side, its initial assembly configuration whole is not affected, and therefore only the flexible membrane 7 and the filter element-absorber 2 are struck or subjected to a collision. Preferably, the outer peripheral portion of the flexible housing 1 may be formed integrally with the outer peripheral portion of the flexible membrane 7, while the inner peripheral portion of the flexible housing 1 may be integrally formed with the outer peripheral portion of the filter-absorber element 2 (not visible) so as to reduce the manufacturing cost. The material for the manufacture of the flexible housing 1 is selected from the group consisting of ethylene / vinyl acetate copolymer resin (EVA), polyethylene terephthalate (PET) and polyvinyl chloride (PVC). or in a combination of the preceding materials. For example, the flexible housing 1 can be made from a single EVA or a combination of PET and PVC. Alternatively, the flexible membrane 7 is made from EVA so as to be hermetically sealed with the flexible housing 1 made from PVC or PET, and vice versa. Although the present invention has been described with reference to the preferred embodiments thereof, it will be apparent to those skilled in the art that various modifications and changes may be made without departing from the scope of the present invention which is understood to be defined by the appended claims.
    权利要求:
    Claims (10)
    [0001]
    CLAIMS1 - A blood filtering device for depleting a content of blood components in blood, characterized in that it comprises: a flexible housing (1) defining a receiving chamber (100) having first and second internal surfaces spaced apart from each other (11, 12) defining said receiving chamber, and first and second outer surfaces (13, 14) respectively opposed to said first and second inner surfaces (11, 12); and a filter-absorber element (2) disposed in said receiving chamber (100), cooperating with said first inner surface (11) to form an inlet guide channel (3) between the two, and cooperating with said second inner surface (12) for forming an outlet guide channel (4) therebetween; an inlet tube (5) having a tip inserted into said first outer surface (13) of said flexible housing (1) so as to establish spatial communication with said inlet guide channel (3); and an outlet tube (6) having a tip inserted into said second outer surface (14) of said flexible housing (1) so as to establish spatial communication with said outlet guide channel (4).
    [0002]
    2 - Blood filtering device according to claim 1, characterized in that said first inner surface (11) comprises a plurality of first plates (111) for guiding fluid. 3028425 14
    [0003]
    3 - Blood filtering device according to claim 1, characterized in that said second inner surface (12) comprises a plurality of second plates (121) for guiding fluid.
    [0004]
    4 - Blood filtering device according to claim 1, characterized in that said first inner surface (11) has a plurality of protrusions (113) for impeding the fluid.
    [0005]
    5 - A blood filtration device according to claim 1, characterized in that said filter-absorber element (2) is disposed in said flexible housing (1) and has a peripheral portion connected to an inner peripheral portion of said flexible housing (1 ).
    [0006]
    6 - A blood filtration device according to claim 1, characterized in that said filter-absorber element (2) has an outer peripheral portion exposed to an outside said flexible housing (1), the blood filtration device further comprising a flexible membrane (7) wrapped around said flexible housing (1), having a peripheral portion formed integrally with said outer peripheral portion of said filter-absorber element (2) such that said flexible housing (1) is fully enclosed in said flexible membrane (7).
    [0007]
    7 - A blood filtration device according to claim 1, characterized in that said flexible housing (1) has an inner peripheral flexible membrane, while said filter-absorber element (2) has an outer peripheral portion formed of a single securing with said inner peripheral flexible membrane of said flexible housing (1) such that said absorbing filter element (2) is disposed in said flexible housing (1). 5
    [0008]
    8 - A blood filtration device according to claim 1, characterized in that said first outer surface (13) of said flexible housing (1) comprises an inlet guide seat (131) projecting outwardly thereof. ci, such that said tip of said inlet tube (5) is integrated into said inlet guide seat (131).
    [0009]
    9 - Blood filtering device according to claim 1, characterized in that said second outer surface (14) of said flexible housing (1) comprises an outlet guide seat (131) projecting outwardly thereof. ci, such that said tip of said outlet tube (6) is integrated into said inlet guide seat (131). 20
    [0010]
    Blood filter device according to claim 1, characterized in that said flexible housing (1) is made from a flexible plastics material, preferably from one of an ethylene / ethylene copolymer resin. vinyl acetate (EVA), polyethylene terephthalate (PET) and polyvinyl chloride (PVC). 30
    类似技术:
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    同族专利:
    公开号 | 公开日
    TWM498020U|2015-04-01|
    FR3028425B1|2019-08-02|
    ITUB201544968U1|2016-12-19|
    CN204656105U|2015-09-23|
    DE202015005215U1|2015-08-26|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    TWI632924B|2017-04-12|2018-08-21|陳尚煒|Blood filter, filtering element thereof and manufacturing method thereof|
    CN108721717B|2017-04-14|2021-01-29|陈尚炜|Blood filter, filter material therefor, and method for producing same|
    CN108721961B|2018-06-12|2021-01-01|广州市雷德生物科技有限公司|Blood filtering device|
    法律状态:
    2016-04-26| PLFP| Fee payment|Year of fee payment: 2 |
    2017-06-12| PLFP| Fee payment|Year of fee payment: 3 |
    2017-09-29| PLSC| Search report ready|Effective date: 20170929 |
    2018-04-27| PLFP| Fee payment|Year of fee payment: 4 |
    2019-05-31| PLFP| Fee payment|Year of fee payment: 5 |
    2020-05-28| PLFP| Fee payment|Year of fee payment: 6 |
    2021-05-28| PLFP| Fee payment|Year of fee payment: 7 |
    优先权:
    申请号 | 申请日 | 专利标题
    TW103220468|2014-11-18|
    TW103220468U|TWM498020U|2014-11-18|2014-11-18|Elastic housing type blood filter|
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